The field of Supramolecular Chemistry has rapidly evolved over the last decades to the point where it now influences a diverse range of research areas, drives technological breakthroughs, and often results in breathtaking feats of ingenuity along the way. None of these advancements would be possible without the creativity and talent of supramolecular chemists throughout the world, and this Research Topic aims to celebrate those scientists as leading experts in the field—the “Suprastars.”